It results from high levels of unconjugated bilirubin in the fetus blood.
Because unconjugated bilirubin are lipid soluble and toxic, it can crosses the blood-brain barrier and it will penetrates neuronal and glial membrane thus cause neurotoxicity.
Because unconjugated bilirubin are lipid soluble and toxic, it can crosses the blood-brain barrier and it will penetrates neuronal and glial membrane thus cause neurotoxicity.
As the fetus’s anemia worsen, the fetus accelerates red cells production
→It leads Liver and spleen to increase in size.
→ As a result, portal hypertension occur, causing the liver to reduces its albumin production.
→ This in turn result in edema.
→ This condition in the fetus is known as hydrops fetalis.
t.
→It leads Liver and spleen to increase in size.
→ As a result, portal hypertension occur, causing the liver to reduces its albumin production.
→ This in turn result in edema.
→ This condition in the fetus is known as hydrops fetalis.
t.